RESUMO
Gold, sulfur and mercurial formulations in Indian alchemy are consumed in conjunction with suitable adjuvant for their synergistic action, reduced toxicity and boosting their bioavailability resulting in improved effectiveness. Poorna chandrodaya chendooram is a well-known mercurial mixture containing gold and sulfur that has traditionally been used to treat a variety of diseases. Fel bovinum purifactum (Gorochanai) is an expectorant. It also acts as a bronchodilator. The second wave mutant virus has better transmission potential and a shorter incubation period than the first wave. Some diabetic patients treated for SARS-CoV-2 with high dose corticosteroids had a decrease in angioinvasive maxillofacial fungal infections (Mucormycosis). Without using synthetic steroids and with optimum oxygen support, this case report emphasizes the therapeutic success of administering Poorna chandirodayam and Gorojanai mathirai together with herbal and herbomineral Siddha formulations in the early inflammatory phase of COVID-19 infection. Five patients with the laboratory-confirmed diagnosis of coronavirus (SARS-CoV-2) infection admitted in the approved Siddha Covid hospital have been involved in the study. Metal-based medications P. chandirodayam and G. mathirai have been demonstrated through these case series to be safe and useful in COVID19.
RESUMO
OBJECTIVE: To investigate the studies on effects of Andrographis paniculata (A. paniculata) (Burm.f.) and Andrographis lineata (A. lineata) nees (Family: Acanthaceae) extracts against two mosquitoes Culex quinquefasciatus (Cx. quinquefasciatus) (Say.) and Aedes aegypti (Ae. aegypti) (Linn.). METHODS: The aqueous and petroleum ether extracts of two plant species, A. paniculata and A. lineate were examined against the larvae of A. aegypti (L.) and Cx. quinquefasciatus with gradually increasing concentration ie. from 50 to 200 ppm of solvent extracts and to test their activity in combination with each other. RESULTS: In a 24 h bioassay experiment with plant extracts, highest mortalities were recorded at 200 ppm of concentrations for leaves of A. lineta and A. paniculata individually. For combination effect, only 150 ppm of the mixture of solvent extracts of petroleum ether: aqueous (1:1) extracts showed 100% mortality after 24 h of exposure. CONCLUSIONS: The results show that, insecticides of plant combination is ecofriend and has better larvicidal activity compared to individual extracts.
